All manuscripts are posted on biorxiv before submission to a journal.

Repression of ferritin light chain translation by human eIF3.

Pulos-Holmes MC, Srole DN, Juarez MG, Lee AS, McSwiggen DT, Ingolia NT, Cate JH.

Elife. 2019 Aug 15;8. pii: e48193. doi: 10.7554/eLife.48193. [Epub ahead of print]

PMID: 31414986

PTBP1 mRNA isoforms and regulation of their translation.

Arake de Tacca LM, Pulos-Holmes MC, Floor SN, Cate JHD.

RNA. 2019 Jul 1. pii: rna.070193.118. doi: 10.1261/rna.070193.118. [Epub ahead of print]

PMID: 31263002

Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.

Li W, Ward FR, McClure KF, Chang ST, Montabana E, Liras S, Dullea RG, Cate JHD.

Nat Struct Mol Biol. 2019 Jun;26(6):501-509. doi: 10.1038/s41594-019-0236-8. Epub 2019 Jun 3.

PMID: 31160784

Overcoming the thermodynamic equilibrium of an isomerization reaction through oxidoreductive reactions for biotransformation.

Liu JJ, Zhang GC, Kwak S, Oh EJ, Yun EJ, Chomvong K, Cate JHD, Jin YS.

Nat Commun. 2019 Mar 22;10(1):1356. doi: 10.1038/s41467-019-09288-6.

PMID: 30902987

Cellular response to small molecules that selectively stall protein synthesis by the ribosome.

Liaud N, Horlbeck MA, Gilbert LA, Gjoni K, Weissman JS, Cate JHD.

PLoS Genet. 2019 Mar 15;15(3):e1008057. doi: 10.1371/journal.pgen.1008057. eCollection 2019 Mar.

PMID: 30875366

Differences in the path to exit the ribosome across the three domains of life.

Dao Duc K, Batra SS, Bhattacharya N, Cate JHD, Song YS.

Nucleic Acids Res. 2019 Feb 26. pii: gkz106. doi: 10.1093/nar/gkz106. [Epub ahead of print]

PMID: 30805621

Bacterial ribosome heterogeneity: Changes in ribosomal protein composition during transition into stationary growth phase.

Lilleorg S, Reier K, Pulk A, Liiv A, Tammsalu T, Peil L, Cate JHD, Remme J.

Biochimie. 2019 Jan;156:169-180. doi: 10.1016/j.biochi.2018.10.013. Epub 2018 Oct 23.

PMID: 30359641

Modulating long-range energetics via helix stabilization: A case study using T4 lysozyme.

Rosemond SN, Hamadani KM, Cate JHD, Marqusee S.

Protein Sci. 2018 Dec;27(12):2084-2093. doi: 10.1002/pro.3521.

PMID: 30284332

Engineering Kluyveromyces marxianus as a Robust Synthetic Biology Platform Host.

Cernak P, Estrela R, Poddar S, Skerker JM, Cheng YF, Carlson AK, Chen B, Glynn VM, Furlan M, Ryan OW, Donnelly MK, Arkin AP, Taylor JW, Cate JHD.

MBio. 2018 Sep 25;9(5). pii: e01410-18. doi: 10.1128/mBio.01410-18.

PMID: 30254120

Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents.

Londregan AT, Wei L, Xiao J, Lintner NG, Petersen D, Dullea RG, McClure KF, Bolt MW, Warmus JS, Coffey SB, Limberakis C, Genovino J, Thuma BA, Hesp KD, Aspnes GE, Reidich B, Salatto CT, Chabot JR, Cate JHD, Liras S, Piotrowski DW.

J Med Chem. 2018 Jul 12;61(13):5704-5718. doi: 10.1021/acs.jmedchem.8b00650. Epub 2018 Jun 25.

PMID: 29878763

Enhanced cellobiose fermentation by engineered Saccharomyces cerevisiae expressing a mutant cellodextrin facilitator and cellobiose phosphorylase.

Kim H, Oh EJ, Lane ST, Lee WH, Cate JHD, Jin YS.

J Biotechnol. 2018 Jun 10;275:53-59. doi: 10.1016/j.jbiotec.2018.04.008. Epub 2018 Apr 13.

PMID: 29660472

Evolutionary engineering improves tolerance for medium-chain alcohols in Saccharomyces cerevisiae.

Davis López SA, Griffith DA, Choi B, Cate JHD, Tullman-Ercek D.

Biotechnol Biofuels. 2018 Apr 2;11:90. doi: 10.1186/s13068-018-1089-9. eCollection 2018.

PMID: 29619086

Programmable RNA recognition using a CRISPR-associated Argonaute.

Lapinaite A, Doudna JA, Cate JHD.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3368-3373. doi: 10.1073/pnas.1717725115. Epub 2018 Mar 12.

PMID: 29531059

Metabolic engineering of yeast for lignocellulosic biofuel production.

Jin YS, Cate JH.

Curr Opin Chem Biol. 2017 Dec;41:99-106. doi: 10.1016/j.cbpa.2017.10.025. Epub 2017 Nov 8. Review.

PMID: 29127883

Role for ribosome-associated complex and stress-seventy subfamily B (RAC-Ssb) in integral membrane protein translation.

Acosta-Sampson L, Döring K, Lin Y, Yu VY, Bukau B, Kramer G, Cate JHD.

J Biol Chem. 2017 Dec 1;292(48):19610-19627. doi: 10.1074/jbc.M117.813857. Epub 2017 Oct 2.

PMID: 28972146

Screening of transporters to improve xylodextrin utilization in the yeast Saccharomyces cerevisiae.

Zhang C, Acosta-Sampson L, Yu VY, Cate JHD.

PLoS One. 2017 Sep 8;12(9):e0184730. doi: 10.1371/journal.pone.0184730. eCollection 2017.

PMID: 28886200

Cellobiose Consumption Uncouples Extracellular Glucose Sensing and Glucose Metabolism in Saccharomyces cerevisiae.

Chomvong K, Benjamin DI, Nomura DK, Cate JHD.

MBio. 2017 Aug 8;8(4). pii: e00855-17. doi: 10.1128/mBio.00855-17.

PMID: 28790206

An in vitro tag-and-modify protein sample generation method for single-molecule fluorescence resonance energy transfer.

Hamadani KM, Howe J, Jensen MK, Wu P, Cate JHD, Marqusee S.

J Biol Chem. 2017 Sep 22;292(38):15636-15648. doi: 10.1074/jbc.M117.791723. Epub 2017 Jul 28.

PMID: 28754692

Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain.

Lintner NG, McClure KF, Petersen D, Londregan AT, Piotrowski DW, Wei L, Xiao J, Bolt M, Loria PM, Maguire B, Geoghegan KF, Huang A, Rolph T, Liras S, Doudna JA, Dullea RG, Cate JH.

PLoS Biol. 2017 Mar 21;15(3):e2001882. doi: 10.1371/journal.pbio.2001882. eCollection 2017 Mar. Erratum in: PLoS Biol. 2018 Apr 17;16(4):e1002628.

PMID: 28323820

Monolayer-crystal streptavidin support films provide an internal standard of cryo-EM image quality.

Han BG, Watson Z, Cate JHD, Glaeser RM.

J Struct Biol. 2017 Dec;200(3):307-313. doi: 10.1016/j.jsb.2017.02.009. Epub 2017 Mar 1.

PMID: 28259651

Human eIF3: from 'blobology' to biological insight.

Cate JH.

Philos Trans R Soc Lond B Biol Sci. 2017 Mar 19;372(1716). pii: 20160176. doi: 10.1098/rstb.2016.0176. Review.

PMID: 28138064

Quantitative determination of ribosome nascent chain stability.

Samelson AJ, Jensen MK, Soto RA, Cate JH, Marqusee S.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13402-13407. Epub 2016 Nov 7.

PMID: 27821780

Internalization of Heterologous Sugar Transporters by Endogenous α-Arrestins in the Yeast Saccharomyces cerevisiae.

Sen A, Acosta-Sampson L, Alvaro CG, Ahn JS, Cate JH, Thorner J.

Appl Environ Microbiol. 2016 Nov 21;82(24):7074-7085. Print 2016 Dec 15.

PMID: 27694235

Relief of Xylose Binding to Cellobiose Phosphorylase by a Single Distal Mutation.

Chomvong K, Lin E, Blaisse M, Gillespie AE, Cate JH.

ACS Synth Biol. 2017 Feb 17;6(2):206-210. doi: 10.1021/acssynbio.6b00211. Epub 2016 Oct 3.

PMID: 27676450

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.

East-Seletsky A, O'Connell MR, Knight SC, Burstein D, Cate JH, Tjian R, Doudna JA.

Nature. 2016 Oct 13;538(7624):270-273. doi: 10.1038/nature19802. Epub 2016 Sep 26.

PMID: 27669025

eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.

Lee AS, Kranzusch PJ, Doudna JA, Cate JH.

Nature. 2016 Jul 27. doi: 10.1038/nature18954.

PMID: 27462815

Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.

Cocozaki AI, Altman RB, Huang J, Buurman ET, Kazmirski SL, Doig P, Prince DB, Blanchard SC, Cate JH, Ferguson AD.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8188-93. doi: 10.1073/pnas.1605127113. Epub 2016 Jul 5.

PMID: 27382179

Bypassing the Pentose Phosphate Pathway: Towards Modular Utilization of Xylose.

Chomvong K, Bauer S, Benjamin DI, Li X, Nomura DK, Cate JH.

PLoS One. 2016 Jun 23;11(6):e0158111. doi: 10.1371/journal.pone.0158111. eCollection 2016.

PMID: 27336308

Long shelf-life streptavidin support-films suitable for electron microscopy of biological macromolecules.

Han BG, Watson Z, Kang H, Pulk A, Downing KH, Cate J, Glaeser RM.

J Struct Biol. 2016 Aug;195(2):238-44. doi: 10.1016/j.jsb.2016.06.009. Epub 2016 Jun 15.

PMID: 27320699

Assembly of eIF3 Mediated by Mutually Dependent Subunit Insertion.

Smith MD, Arake-Tacca L, Nitido A, Montabana E, Park A, Cate JH.

Structure. 2016 Jun 7;24(6):886-96. doi: 10.1016/j.str.2016.02.024. Epub 2016 May 19.

PMID: 27210288

STRUCTURE. A Big Bang in spliceosome structural biology.

Cate JH.

Science. 2016 Mar 25;351(6280):1390-2. doi: 10.1126/science.aaf4465.

PMID: 27013712

Editorial overview: Energy biotechnology.

Cate JH, Ball AS.

Curr Opin Biotechnol. 2016 Apr;38:v-vii. doi: 10.1016/j.copbio.2016.02.019. Epub 2016 Mar 7.

PMID: 26965392

Energy biotechnology in the CRISPR-Cas9 era.

Estrela R, Cate JH.

Curr Opin Biotechnol. 2016 Apr;38:79-84. doi: 10.1016/j.copbio.2016.01.005. Epub 2016 Feb 10. Review.

PMID: 26874259

Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation.

Thakor N, Smith MD, Roberts L, Faye MD, Patel H, Wieden HJ, Cate JH, Holcik M.

RNA Biol. 2016 Feb 1:1-15. doi: 10.1080/15476286.2015.1137419

PMID: 26828225

Factors that Influence the Formation and Stability of Thin, Cryo-EM Specimens.

Glaeser RM, Han BG, Csencsits R, Killilea A, Pulk A, Cate JH.

Biophys J. 2015 Sep 16. pii: S0006-3495(15)00813-9. doi: 10.1016/j.bpj.2015.07.050. [Epub ahead of print] Review.

PMID: 26386606

Cellobionic acid utilization: from Neurospora crassa to Saccharomyces cerevisiae.

Li X, Chomvong K, Yu VY, Liang JM, Lin Y, Cate JH.

Biotechnol Biofuels. 2015 Aug 16;8:120. doi: 10.1186/s13068-015-0303-2. eCollection 2015.

PMID: 26279678

Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.

Wasserman MR, Pulk A, Zhou Z, Altman RB, Zinder JC, Green KD, Garneau-Tsodikova S, Doudna Cate JH, Blanchard SC.

Nat Commun. 2015 Jul 30;6:7896. doi: 10.1038/ncomms8896.

PMID: 26224058

eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.

Lee AS, Kranzusch PJ, Cate JH.

Nature. 2015 Jun 4;522(7554):111-4. doi: 10.1038/nature14267. Epub 2015 Apr 6.

PMID: 25849773

High-resolution structure of the Escherichia coli ribosome.

Noeske J, Wasserman MR, Terry DS, Altman RB, Blanchard SC, Cate JH.

Nat Struct Mol Biol. 2015 Apr;22(4):336-41. doi: 10.1038/nsmb.2994. Epub 2015 Mar 16.

PMID: 25775265

Expanding xylose metabolism in yeast for plant cell wall conversion to biofuels.

Li X, Yu VY, Lin Y, Chomvong K, Estrela R, Park A, Liang JM, Znameroski EA, Feehan J, Kim SR, Jin YS, Glass NL, Cate JH.

Elife. 2015 Feb 3;4. doi: 10.7554/eLife.05896.

PMID: 25647728

Simultaneous utilization of cellobiose, xylose, and acetic acid from lignocellulosic biomass for biofuel production by an engineered yeast platform.

Wei N, Oh EJ, Million G, Cate JH, Jin YS.

ACS Synth Biol. 2015 Jun 19;4(6):707-13. doi: 10.1021/sb500364q. Epub 2015 Jan 27.

PMID: 25587748

Microbial biosynthesis of medium-chain 1-alkenes by a nonheme iron oxidase.

Rui Z, Li X, Zhu X, Liu J, Domigan B, Barr I, Cate JH, Zhang W.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18237-42. doi: 10.1073/pnas.1419701112. Epub 2014 Dec 8.

PMID: 25489112

Leveraging transcription factors to speed cellobiose fermentation by Saccharomyces cerevisiae.

Lin Y, Chomvong K, Acosta-Sampson L, Estrela R, Galazka JM, Kim SR, Jin YS, Cate JH.

Biotechnol Biofuels. 2014 Aug 27;7(1):126. doi: 10.1186/s13068-014-0126-6. eCollection 2014.

PMID: 25435910

Multiplex engineering of industrial yeast genomes using CRISPRm.

Ryan OW, Cate JH.

Methods Enzymol. 2014;546:473-89. doi: 10.1016/B978-0-12-801185-0.00023-4.

PMID: 25398354

Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.

Olivier NB, Altman RB, Noeske J, Basarab GS, Code E, Ferguson AD, Gao N, Huang J, Juette MF, Livchak S, Miller MD, Prince DB, Cate JH, Buurman ET, Blanchard SC.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16274-9. doi: 10.1073/pnas.1414401111. Epub 2014 Nov 3.

PMID: 25368144

Construction of a quadruple auxotrophic mutant of an industrial polyploid Saccharomyces cerevisiae strain by using RNA-guided Cas9 nuclease.

Zhang GC, Kong II, Kim H, Liu JJ, Cate JH, Jin YS.

Appl Environ Microbiol. 2014 Dec;80(24):7694-701. doi: 10.1128/AEM.02310-14. Epub 2014 Oct 3.

PMID: 25281382

Selection of chromosomal DNA libraries using a multiplex CRISPR system.

Ryan OW, Skerker JM, Maurer MJ, Li X, Tsai JC, Poddar S, Lee ME, DeLoache W, Dueber JE, Arkin AP, Cate JH.

Elife. 2014 Aug 19;3. doi: 10.7554/eLife.03703.

PMID: 25139909

Synergy of streptogramin antibiotics occurs independently of their effects on translation.

Noeske J, Huang J, Olivier NB, Giacobbe RA, Zambrowski M, Cate JH.

Antimicrob Agents Chemother. 2014 Sep;58(9):5269-79. doi: 10.1128/AAC.03389-14. Epub 2014 Jun 23.

PMID: 24957822

Overcoming inefficient cellobiose fermentation by cellobiose phosphorylase in the presence of xylose.

Chomvong K, Kordić V, Li X, Bauer S, Gillespie AE, Ha SJ, Oh EJ, Galazka JM, Jin YS, Cate JH.

Biotechnol Biofuels. 2014 Jun 7;7:85. doi: 10.1186/1754-6834-7-85. eCollection 2014.

PMID: 24944578

The proteome and phosphoproteome of Neurospora crassa in response to cellulose, sucrose and carbon starvation.

Xiong Y, Coradetti ST, Li X, Gritsenko MA, Clauss T, Petyuk V, Camp D, Smith R, Cate JH, Yang F, Glass NL.

Fungal Genet Biol. 2014 Nov;72:21-33. doi: 10.1016/j.fgb.2014.05.005. Epub 2014 May 29.

PMID: 24881580

2,3-butanediol production from cellobiose by engineered Saccharomyces cerevisiae.

Nan H, Seo SO, Oh EJ, Seo JH, Cate JH, Jin YS.

Appl Microbiol Biotechnol. 2014 Jun;98(12):5757-64. doi: 10.1007/s00253-014-5683-x. Epub 2014 Apr 18.

PMID: 24743979

Regulating the ribosome: a spotlight on RNA dark matter.

Lintner NG, Cate JH.

Mol Cell. 2014 Apr 10;54(1):1-2. doi: 10.1016/j.molcel.2014.03.042.

PMID: 24725592

A new system for naming ribosomal proteins.

Ban N, Beckmann R, Cate JH, Dinman JD, Dragon F, Ellis SR, Lafontaine DL, Lindahl L, Liljas A, Lipton JM, McAlear MA, Moore PB, Noller HF, Ortega J, Panse VG, Ramakrishnan V, Spahn CM, Steitz TA, Tchorzewski M, Tollervey D, Warren AJ, Williamson JR, Wilson D, Yonath A, Yusupov M.

Curr Opin Struct Biol. 2014 Feb;24:165-9. doi: 10.1016/ Epub 2014 Feb 10. Review.

PMID: 24524803

Determinants of regioselective hydroxylation in the fungal polysaccharide monooxygenases.

Vu VV, Beeson WT, Phillips CM, Cate JH, Marletta MA.

J Am Chem Soc. 2014 Jan 15;136(2):562-5. doi: 10.1021/ja409384b. Epub 2013 Dec 26.

PMID: 24350607

Evidence for transceptor function of cellodextrin transporters in Neurospora crassa.

Znameroski EA, Li X, Tsai JC, Galazka JM, Glass NL, Cate JH.

J Biol Chem. 2014 Jan 31;289(5):2610-9. doi: 10.1074/jbc.M113.533273. Epub 2013 Dec 16.

PMID: 24344125

Human-like eukaryotic translation initiation factor 3 from Neurospora crassa.

Smith MD, Gu Y, Querol-Audí J, Vogan JM, Nitido A, Cate JH.

PLoS One. 2013 Nov 8;8(11):e78715. doi: 10.1371/journal.pone.0078715. eCollection 2013.

PMID: 24250809

Analysis of cellodextrin transporters from Neurospora crassa in Saccharomyces cerevisiae for cellobiose fermentation.

Kim H, Lee WH, Galazka JM, Cate JH, Jin YS.

Appl Microbiol Biotechnol. 2014 Feb;98(3):1087-94. doi: 10.1007/s00253-013-5339-2. Epub 2013 Nov 5.

PMID: 24190499

Continuous co-fermentation of cellobiose and xylose by engineered Saccharomyces cerevisiae.

Ha SJ, Kim SR, Kim H, Du J, Cate JH, Jin YS.

Bioresour Technol. 2013 Dec;149:525-31. doi: 10.1016/j.biortech.2013.09.082. Epub 2013 Sep 27.

PMID: 24140899

Enhanced biofuel production through coupled acetic acid and xylose consumption by engineered yeast.

Wei N, Quarterman J, Kim SR, Cate JH, Jin YS.

Nat Commun. 2013;4:2580. doi: 10.1038/ncomms3580.

PMID: 24105024

Draft Genome Sequence of the Cellulolytic Bacterium Clostridium papyrosolvens C7 (ATCC 700395).

Zepeda V, Dassa B, Borovok I, Lamed R, Bayer EA, Cate JH.

Genome Announc. 2013 Sep 12;1(5). pii: e00698-13. doi: 10.1128/genomeA.00698-13.

PMID: 24029755

Investigation of the functional role of aldose 1-epimerase in engineered cellobiose utilization.

Li S, Ha SJ, Kim HJ, Galazka JM, Cate JH, Jin YS, Zhao H.

J Biotechnol. 2013 Oct 10;168(1):1-6. doi: 10.1016/j.jbiotec.2013.08.003. Epub 2013 Aug 14.

PMID: 23954547

Control of ribosomal subunit rotation by elongation factor G.

Pulk A, Cate JH.

Science. 2013 Jun 28;340(6140):1235970. doi: 10.1126/science.1235970.

PMID: 23812721

Plant cell wall deconstruction by ascomycete fungi.

Glass NL, Schmoll M, Cate JH, Coradetti S.

Annu Rev Microbiol. 2013;67:477-98. doi: 10.1146/annurev-micro-092611-150044. Epub 2013 Jun 28. Review.

PMID: 23808333

Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation.

Sun C, Querol-Audí J, Mortimer SA, Arias-Palomo E, Doudna JA, Nogales E, Cate JH.

Nucleic Acids Res. 2013 Aug;41(15):7512-21. doi: 10.1093/nar/gkt510. Epub 2013 Jun 13.

PMID: 23766293

Architecture of human translation initiation factor 3.

Querol-Audi J, Sun C, Vogan JM, Smith MD, Gu Y, Cate JH, Nogales E.

Structure. 2013 Jun 4;21(6):920-8. doi: 10.1016/j.str.2013.04.002. Epub 2013 Apr 25.

PMID: 23623729

Connecting the kinetics and energy landscape of tRNA translocation on the ribosome.

Whitford PC, Blanchard SC, Cate JH, Sanbonmatsu KY.

PLoS Comput Biol. 2013;9(3):e1003003. doi: 10.1371/journal.pcbi.1003003. Epub 2013 Mar 21.

PMID: 23555233

Single amino acid substitutions in HXT2.4 from Scheffersomyces stipitis lead to improved cellobiose fermentation by engineered Saccharomyces cerevisiae.

Ha SJ, Kim H, Lin Y, Jang MU, Galazka JM, Kim TJ, Cate JH, Jin YS.

Appl Environ Microbiol. 2013 Mar;79(5):1500-7. doi: 10.1128/AEM.03253-12. Epub 2012 Dec 21.

PMID: 23263959

Energetic benefits and rapid cellobiose fermentation by Saccharomyces cerevisiae expressing cellobiose phosphorylase and mutant cellodextrin transporters.

Ha SJ, Galazka JM, Joong Oh E, Kordić V, Kim H, Jin YS, Cate JH.

Metab Eng. 2013 Jan;15:134-43. doi: 10.1016/j.ymben.2012.11.005. Epub 2012 Nov 22.

PMID: 23178501

Enhanced xylitol production through simultaneous co-utilization of cellobiose and xylose by engineered Saccharomyces cerevisiae.

Oh EJ, Ha SJ, Rin Kim S, Lee WH, Galazka JM, Cate JH, Jin YS.

Metab Eng. 2013 Jan;15:226-34. doi: 10.1016/j.ymben.2012.09.003. Epub 2012 Oct 24.

PMID: 23103205

Allosteric control of the ribosome by small-molecule antibiotics.

Wang L, Pulk A, Wasserman MR, Feldman MB, Altman RB, Cate JH, Blanchard SC.

Nat Struct Mol Biol. 2012 Sep;19(9):957-63. doi: 10.1038/nsmb.2360. Epub 2012 Aug 19.

PMID: 22902368

Structural basis for protein synthesis: snapshots of the ribosome in motion.

Noeske J, Cate JH.

Curr Opin Struct Biol. 2012 Dec;22(6):743-9. doi: 10.1016/ Epub 2012 Aug 4. Review.

PMID: 22871550

Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases.

Li X, Beeson WT 4th, Phillips CM, Marletta MA, Cate JH.

Structure. 2012 Jun 6;20(6):1051-61. doi: 10.1016/j.str.2012.04.002. Epub 2012 May 10.

PMID: 22578542

The structure and function of the eukaryotic ribosome.

Wilson DN, Doudna Cate JH.

Cold Spring Harb Perspect Biol. 2012 May 1;4(5). pii: a011536. doi: 10.1101/cshperspect.a011536. Review.

PMID: 22550233

The mechanisms of RNA SHAPE chemistry.

McGinnis JL, Dunkle JA, Cate JH, Weeks KM.

J Am Chem Soc. 2012 Apr 18;134(15):6617-24. doi: 10.1021/ja2104075. Epub 2012 Apr 5. Erratum in: J Am Chem Soc. 2012 Jul 25;134(29):12319.

PMID: 22475022

Induction of lignocellulose-degrading enzymes in Neurospora crassa by cellodextrins.

Znameroski EA, Coradetti ST, Roche CM, Tsai JC, Iavarone AT, Cate JH, Glass NL.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6012-7. doi: 10.1073/pnas.1118440109. Epub 2012 Apr 2.

PMID: 22474347

Model-guided strain improvement: simultaneous hydrolysis and co-fermentation of cellulosic sugars.

Jin YS, Cate JH.

Biotechnol J. 2012 Mar;7(3):328-9. doi: 10.1002/biot.201100489. No abstract available.

PMID: 22383191

Oxidative cleavage of cellulose by fungal copper-dependent polysaccharide monooxygenases.

Beeson WT, Phillips CM, Cate JH, Marletta MA.

J Am Chem Soc. 2012 Jan 18;134(2):890-2. doi: 10.1021/ja210657t. Epub 2011 Dec 28.

PMID: 22188218

Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3).

Sun C, Todorovic A, Querol-Audí J, Bai Y, Villa N, Snyder M, Ashchyan J, Lewis CS, Hartland A, Gradia S, Fraser CS, Doudna JA, Nogales E, Cate JH.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20473-8. doi: 10.1073/pnas.1116821108. Epub 2011 Dec 1.

PMID: 22135459

Cellobiose dehydrogenase and a copper-dependent polysaccharide monooxygenase potentiate cellulose degradation by Neurospora crassa.

Phillips CM, Beeson WT, Cate JH, Marletta MA.

ACS Chem Biol. 2011 Dec 16;6(12):1399-406. doi: 10.1021/cb200351y. Epub 2011 Oct 25.

PMID: 22004347

Cofermentation of cellobiose and galactose by an engineered Saccharomyces cerevisiae strain.

Ha SJ, Wei Q, Kim SR, Galazka JM, Cate JH, Jin YS.

Appl Environ Microbiol. 2011 Aug 15;77(16):5822-5. doi: 10.1128/AEM.05228-11. Epub 2011 Jun 24. Erratum in: Appl Environ Microbiol. 2011 Oct;77(20):7438. Cate, Jamie [corrected to Cate, Jamie H D].

PMID: 21705527

A new diet for yeast to improve biofuel production.

Galazka JM, Cate JH.

Bioeng Bugs. 2011 Jul-Aug;2(4):199-202. doi: 10.4161/bbug.2.4.15624. Epub 2011 Jul 1.

PMID: 21637011

Structures of the bacterial ribosome in classical and hybrid states of tRNA binding.

Dunkle JA, Wang L, Feldman MB, Pulk A, Chen VB, Kapral GJ, Noeske J, Richardson JS, Blanchard SC, Cate JH.

Science. 2011 May 20;332(6032):981-4. doi: 10.1126/science.1202692.

PMID: 21596992

Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation.

Ha SJ, Galazka JM, Kim SR, Choi JH, Yang X, Seo JH, Glass NL, Cate JH, Jin YS.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):504-9. doi: 10.1073/pnas.1010456108. Epub 2010 Dec 27.

PMID: 21187422

Extracellular aldonolactonase from Myceliophthora thermophila.

Beeson WT 4th, Iavarone AT, Hausmann CD, Cate JH, Marletta MA.

Appl Environ Microbiol. 2011 Jan;77(2):650-6. doi: 10.1128/AEM.01922-10. Epub 2010 Nov 12.

PMID: 21075873

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.

Dunkle JA, Xiong L, Mankin AS, Cate JH.

Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17152-7. doi: 10.1073/pnas.1007988107. Epub 2010 Sep 27.

PMID: 20876128

Overcoming glucose repression in mixed sugar fermentation by co-expressing a cellobiose transporter and a β-glucosidase in Saccharomyces cerevisiae.

Li S, Du J, Sun J, Galazka JM, Glass NL, Cate JH, Yang X, Zhao H.

Mol Biosyst. 2010 Nov;6(11):2129-32. doi: 10.1039/c0mb00063a. Epub 2010 Sep 27.

PMID: 20871937

Hepatitis C virus core-derived peptides inhibit genotype 1b viral genome replication via interaction with DDX3X.

Sun C, Pager CT, Luo G, Sarnow P, Cate JH.

PLoS One. 2010 Sep 17;5(9). pii: e12826. doi: 10.1371/journal.pone.0012826.

PMID: 20862261

Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis.

Llano-Sotelo B, Dunkle J, Klepacki D, Zhang W, Fernandes P, Cate JH, Mankin AS.

Antimicrob Agents Chemother. 2010 Dec;54(12):4961-70. doi: 10.1128/AAC.00860-10. Epub 2010 Sep 20.

PMID: 20855725

Cellodextrin transport in yeast for improved biofuel production.

Galazka JM, Tian C, Beeson WT, Martinez B, Glass NL, Cate JH.

Science. 2010 Oct 1;330(6000):84-6. doi: 10.1126/science.1192838. Epub 2010 Sep 9.

PMID: 20829451

Distinct regions of human eIF3 are sufficient for binding to the HCV IRES and the 40S ribosomal subunit.

Cai Q, Todorovic A, Andaya A, Gao J, Leary JA, Cate JH.

J Mol Biol. 2010 Oct 22;403(2):185-96. doi: 10.1016/j.jmb.2010.07.054. Epub 2010 Sep 15.

PMID: 20816988

Ribosome structure and dynamics during translocation and termination.

Dunkle JA, Cate JH.

Annu Rev Biophys. 2010;39:227-44. doi: 10.1146/annurev.biophys.37.032807.125954. Review.

PMID: 20192776

Some reassembly required.

Cate JH.

Mol Microbiol. 2010 Feb;75(4):793-4. doi: 10.1111/j.1365-2958.2009.07017.x. Epub 2009 Dec 16.

PMID: 20025660

Systems analysis of plant cell wall degradation by the model filamentous fungus Neurospora crassa.

Tian C, Beeson WT, Iavarone AT, Sun J, Marletta MA, Cate JH, Glass NL.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22157-62. doi: 10.1073/pnas.0906810106. Epub 2009 Dec 15.

PMID: 20018766

Spontaneous formation of the unlocked state of the ribosome is a multistep process.

Munro JB, Altman RB, Tung CS, Cate JH, Sanbonmatsu KY, Blanchard SC.

Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):709-14. doi: 10.1073/pnas.0908597107. Epub 2009 Dec 17.

PMID: 20018653

Structures of the ribosome in intermediate states of ratcheting.

Zhang W, Dunkle JA, Cate JH.

Science. 2009 Aug 21;325(5943):1014-7. doi: 10.1126/science.1175275.

PMID: 19696352

Structural basis for hygromycin B inhibition of protein biosynthesis.

Borovinskaya MA, Shoji S, Fredrick K, Cate JH.

RNA. 2008 Aug;14(8):1590-9. doi: 10.1261/rna.1076908. Epub 2008 Jun 20.

PMID: 18567815

Structural Insights into ribosome recycling factor interactions with the 70S ribosome.

Pai RD, Zhang W, Schuwirth BS, Hirokawa G, Kaji H, Kaji A, Cate JH.

J Mol Biol. 2008 Mar 7;376(5):1334-47. doi: 10.1016/j.jmb.2007.12.048. Epub 2008 Jan 3.

PMID: 18234219

Chemical biology at Berkeley.

Francis MB, Doudna Cate JH.

ACS Chem Biol. 2007 Nov 20;2(11):702-5. No abstract available.

PMID: 18030983

A steric block in translation caused by the antibiotic spectinomycin.

Borovinskaya MA, Shoji S, Holton JM, Fredrick K, Cate JH.

ACS Chem Biol. 2007 Aug 17;2(8):545-52. Epub 2007 Aug 10.

PMID: 17696316

Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.

Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS, Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH.

Nat Struct Mol Biol. 2007 Aug;14(8):727-32. Epub 2007 Jul 29.

PMID: 17660832

Insights into protein biosynthesis from structures of bacterial ribosomes.

Berk V, Cate JH.

Curr Opin Struct Biol. 2007 Jun;17(3):302-9. Epub 2007 Jun 15. Review.

PMID: 17574829

Structural basis for mRNA and tRNA positioning on the ribosome.

Berk V, Zhang W, Pai RD, Cate JH.

Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15830-4. Epub 2006 Oct 12. Erratum in: Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19931. Cate, Jamie H Doudna [corrected to Cate, Jamie H D].

PMID: 17038497

Structural analysis of kasugamycin inhibition of translation.

Schuwirth BS, Day JM, Hau CW, Janssen GR, Dahlberg AE, Cate JH, Vila-Sanjurjo A.

Nat Struct Mol Biol. 2006 Oct;13(10):879-86. Epub 2006 Sep 24.

PMID: 16998486

Mixing crowded biological solutions in milliseconds.

Liau A, Karnik R, Majumdar A, Cate JH.

Anal Chem. 2005 Dec 1;77(23):7618-25.

PMID: 16316169

Accessibility of 18S rRNA in human 40S subunits and 80S ribosomes at physiological magnesium ion concentrations--implications for the study of ribosome dynamics.

Shenvi CL, Dong KC, Friedman EM, Hanson JA, Cate JH.

RNA. 2005 Dec;11(12):1898-908.

PMID: 16314459

Structures of the bacterial ribosome at 3.5 A resolution.

Schuwirth BS, Borovinskaya MA, Hau CW, Zhang W, Vila-Sanjurjo A, Holton JM, Cate JH.

Science. 2005 Nov 4;310(5749):827-34.

PMID: 16272117

The ins and outs of protein synthesis.

Cate JH.

Structure. 2005 Nov;13(11):1584-5. No abstract available.

PMID: 16271881

Structural basis for the control of translation initiation during stress.

Vila-Sanjurjo A, Schuwirth BS, Hau CW, Cate JH.

Nat Struct Mol Biol. 2004 Nov;11(11):1054-9. Epub 2004 Oct 24. Erratum in: Nat Struct Mol Biol. 2007 Apr;14(4):351.

PMID: 15502846

A conformational switch controls hepatitis delta virus ribozyme catalysis.

Ke A, Zhou K, Ding F, Cate JH, Doudna JA.

Nature. 2004 May 13;429(6988):201-5.

PMID: 15141216

X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli.

Vila-Sanjurjo A, Ridgeway WK, Seymaner V, Zhang W, Santoso S, Yu K, Cate JH.

Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8682-7. Epub 2003 Jul 9.

PMID: 12853578

Structure of the ribosome at 5.5 A resolution and its interactions with functional ligands.

Noller HF, Yusupov MM, Yusupova GZ, Baucom A, Lieberman K, Lancaster L, Dallas A, Fredrick K, Earnest TN, Cate JH.

Cold Spring Harb Symp Quant Biol. 2001;66:57-66. Review. No abstract available.

PMID: 12762008

Translocation of tRNA during protein synthesis.

Noller HF, Yusupov MM, Yusupova GZ, Baucom A, Cate JH.

FEBS Lett. 2002 Mar 6;514(1):11-6. Review.

PMID: 11904173

Construction of low-resolution x-ray crystallographic electron density maps of the ribosome.

Cate JH.

Methods. 2001 Nov;25(3):303-8.

PMID: 11860284

The path of messenger RNA through the ribosome.

Yusupova GZ, Yusupov MM, Cate JH, Noller HF.

Cell. 2001 Jul 27;106(2):233-41.

PMID: 11511350

Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21.

Gregory ST, Cate JH, Dahlberg AE.

J Bacteriol. 2001 Jul;183(14):4382-5.

PMID: 11418580

Streptomycin-resistant and streptomycin-dependent mutants of the extreme thermophile Thermus thermophilus.

Gregory ST, Cate JH, Dahlberg AE.

J Mol Biol. 2001 Jun 1;309(2):333-8.

PMID: 11371156

Crystal structure of the ribosome at 5.5 A resolution.

Yusupov MM, Yusupova GZ, Baucom A, Lieberman K, Earnest TN, Cate JH, Noller HF.

Science. 2001 May 4;292(5518):883-96. Epub 2001 Mar 29.

PMID: 11283358

The location of protein S8 and surrounding elements of 16S rRNA in the 70S ribosome from combined use of directed hydroxyl radical probing and X-ray crystallography.

Lancaster L, Culver GM, Yusupova GZ, Cate JH, Yusupov MM, Noller HF.

RNA. 2000 May;6(5):717-29.

PMID: 10836793

Solving large RNA structures by X-ray crystallography.

Cate JH, Doudna JA.

Methods Enzymol. 2000;317:169-80. No abstract available.

PMID: 10829280

Identification of an RNA-protein bridge spanning the ribosomal subunit interface.

Culver GM, Cate JH, Yusupova GZ, Yusupov MM, Noller HF.

Science. 1999 Sep 24;285(5436):2133-6.

PMID: 10497132

X-ray crystal structures of 70S ribosome functional complexes.

Cate JH, Yusupov MM, Yusupova GZ, Earnest TN, Noller HF.

Science. 1999 Sep 24;285(5436):2095-104.

PMID: 10497122

A specific monovalent metal ion integral to the AA platform of the RNA tetraloop receptor.

Basu S, Rambo RP, Strauss-Soukup J, Cate JH, Ferré-D'Amaré AR, Strobel SA, Doudna JA.

Nat Struct Biol. 1998 Nov;5(11):986-92.

PMID: 9808044

Complementary sets of noncanonical base pairs mediate RNA helix packing in the group I intron active site.

Strobel SA, Ortoleva-Donnelly L, Ryder SP, Cate JH, Moncoeur E.

Nat Struct Biol. 1998 Jan;5(1):60-6.

PMID: 9437431

A magnesium ion core at the heart of a ribozyme domain.

Cate JH, Hanna RL, Doudna JA.

Nat Struct Biol. 1997 Jul;4(7):553-8.

PMID: 9228948

RNA structure: crystal clear?

Doudna JA, Cate JH.

Curr Opin Struct Biol. 1997 Jun;7(3):310-6. Review.

PMID: 9204271

A sparse matrix approach to crystallizing ribozymes and RNA motifs.

Cate JH, Doudna JA.

Methods Mol Biol. 1997;74:379-86. No abstract available.

PMID: 9204453

Metal-binding sites in the major groove of a large ribozyme domain.

Cate JH, Doudna JA.

Structure. 1996 Oct 15;4(10):1221-9.

PMID: 8939748

RNA tertiary structure mediation by adenosine platforms.

Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Szewczak AA, Kundrot CE, Cech TR, Doudna JA.

Science. 1996 Sep 20;273(5282):1696-9.

PMID: 8781229

Crystal structure of a group I ribozyme domain: principles of RNA packing.

Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Kundrot CE, Cech TR, Doudna JA.

Science. 1996 Sep 20;273(5282):1678-85.

PMID: 8781224